Amino acids in formation of collagen
Collagen contains specific amino acids – Glycine, Proline, Hydroxyproline and Arginine. These amino acids have a regular arrangement in each of the three chains of these collagen subunits.
膠原蛋白形成中的氨基酸
膠原蛋白含有特定的氨基酸——甘氨酸、脯氨酸、羥脯氨酸和精氨酸。 這些氨基酸在這些膠原亞基的三個鏈中的每一個中都有規則排列。
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Glycine, proline, and hydroxyproline (Hyp) contribute to 57% of total amino acids (AAs) in collagen
甘氨酸、脯氨酸和羥脯氨酸 (Hyp) 佔膠原蛋白中總氨基酸 (AA) 的 57%
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro
高甘氨酸濃度增加體外關節軟骨細胞的膠原合成
Thus, increasing glycine in the diet may well be a strategy for helping cartilage regeneration by enhancing collagen synthesis
因此,增加飲食中的甘氨酸很可能是一種通過增強膠原蛋白合成來幫助軟骨再生的策略
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The study found that glycine supplementation caused quantitatively higher collagen expression
研究發現,甘氨酸補充劑導致膠原蛋白表達量增加
2002a; Stoll et al. 1992). Arginine also improves wound healing by increasing collagen synthesis;
2002a; 斯托爾等人。 1992). 精氨酸還通過增加膠原蛋白合成來促進傷口癒合;
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Arginine-induced collagen production by smooth muscle cells was found to be dependent on conversion of arginine to proline (94)
發現平滑肌細胞精氨酸誘導的膠原蛋白生成依賴於精氨酸向脯氨酸的轉化 (94)
富含甘氨酸的蔬菜:
大豆、海苔(海藻)、扁豆、利馬豆
富含脯氨酸的蔬菜:
大豆,馬鈴薯,白菜,扁豆
富含精氨酸的蔬菜:
大豆,大蒜,豌豆,扁豆,利馬豆
Although glutamine (Gln) is known as an important stimulator of collagen biosynthesis in collagen-producing cells
儘管谷氨酰胺 (Gln) 被認為是膠原蛋白生成細胞中膠原蛋白生物合成的重要刺激物
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glutamine stimulates collagen synthesis through the conversion process
谷氨酰胺通過轉化過程刺激膠原蛋白合成
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Amino acids regulate protein metabolism, glutamine stimulates collagen synthesis through the conversion process to proline and provides 75 % of the intracellular free proline in fibroblasts.
氨基酸調節蛋白質代謝,谷氨酰胺通過轉化為脯氨酸的過程刺激膠原蛋白合成,並在成纖維細胞中提供 75% 的細胞內游離脯氨酸。
Lysine modifications of collagen are highly complicated sequential processes catalysed by several groups of enzymes leading to the final step of biosynthesis, covalent intermolecular cross-linking.
膠原蛋白的賴氨酸修飾是高度複雜的連續過程,由幾組酶催化,導致生物合成的最後一步,共價分子間交聯。
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The amount of lysine in collagen is only 3 or 4% of total aminoacids, but it has an important function in the constitution of the cross-links between the molecules to built the fibrils and the fibers of collagen.
膠原蛋白中賴氨酸的含量僅為氨基酸總量的3%或4%,但它在分子間交聯的構成中具有重要作用,可構成膠原蛋白的原纖維和纖維。
富含賴氨酸的蔬菜:
大豆,扁豆,豌豆,利馬豆,馬鈴薯
A high level of sulfate utilization occurs during collagen synthesis [6]
膠原蛋白合成過程中會發生高水平的硫酸鹽利用 [6]
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Studies have shown that methionine is an important amino acid for collagen synthesis [48]
研究表明蛋氨酸(甲硫胺酸)是膠原蛋白合成的重要氨基酸 [48]
節錄自https://www.mdpi.com/2076-2615/12/15/1950/pdf(網址會自動下載僅供參考)
富含蛋氨酸的蔬菜:
大豆,紫菜,馬鈴薯,螺旋藻,玉米,扁豆,豌豆